Sisyphus Prime is the second and final boss of [ P-2: WAIT OF THE WORLD ]. V1's disturbance of the Flesh Panopticon awakens him, breaking free from it himself before V1 can defeat it. When released, Sisyphus speaks of his intention to wreak destruction upon heaven and acknowledges the machine's actions in the previous Prime Sanctum, admitting curiosity for the one that had slain Minos Prime. He is considered the most complex and difficult boss of Act II and in the game so far.

"A Visitor? mm.. indeed. i have slept long enough."