Sedusa is a beautiful mistress supervillain gorgon of disguise, and a recurring antagonist for seductress who uses her feminine wiles and quick wits to influence men to do her bidding and an enemy of the Powerpuff Girls. When her identity is revealed, she often fights with her whip-like hair which she can lengthen and control in a variety of offensive ways on her opponents. Her name and snake-like hair are obviously inspired by Medusa. For a brief period, she was Professor Utonium's girlfriend under the alias Ima Goodelady.

Sedusa is a beautiful mistress of disguise. She is a seductress who uses her feminine wiles and quick wits to influence men to do her bidding. When her identity is revealed, she often fights with her whip-like hair which she can lengthen and control in a variety of offensive ways on her opponents. She usually speaks in a harsh, angry voice, but switches it to a soft, maternalistic voice when around the Professor. Her name and snake-like hair are inspired by Medusa.

For a brief period, she was Professor Utonium's girlfriend under the alias "Ima Goodelady."

Sedusa is a tall, beautiful, paste-white-skinned humanoid-woman with an hourglass figure, freckles on her face, pointed ears, lime-green eyes and long, black hair with maroon-red accents, which writhes around in all directions like slithering snakes. She also wore red lipstick on her lips for makeup.

In terms of attire, Sedusa sported a red-black color scheme on her clothing, which consists of a red leotard, red opera gloves, red fishnet stockings over black pantyhose, and red thigh-high, high-heeled boots.

While disguised as Ima Goodelady, Sedusa takes the form of a pale-skinned woman with platinum-blonde/white hair with light pink streaks, kept in a bob style, and wears dark pink lipstick for her makeup. Her outfits features color schemes going from white, light pinks, darker-pinks, all the way to red, which slowly foreshadows her true colors. Similarities with her true form are her freckles, body figure and eye color.

In "Something's a Ms.", Sedusa disguises herself as Ms. Bellum, appearing completely identical to the secretary. As she wears Ms. Bellum's business attire and accessories, she also wears long, tan socks to have her pale-skinned legs appear tan-colored like Ms. Bellum's, possibly tan-colored gloves or bodypaint on her hands, possibly tan-colored bodypaint on her chest and a mask/wig made to replicate Ms. Bellum's hair and hidden face.

When disguised as Madge in "Hell Toupee", she wears a 1950’s styled light blue dress with matching pumps and a large light orange wig with a blue hairbow in the center.

Reference: https://powerpuffgirls.fandom.com/wiki/Sedusa_(1998_TV_series)