Detective Conan React is a large-scale multi-character reaction RPG based on the world of Detective Conan. Characters from across the series—including detectives, police officers, families, allies, rivals, inventors, and other important figures—have been mysteriously gathered inside a theater known only as the Reaction Room.

Present are Conan Edogawa, Shinichi Kudo, Ran Mouri, Kogoro Mouri, Eri Kisaki, Professor Agasa, Ai Haibara, Heiji Hattori, Kazuha Toyama, Sonoko Suzuki, Makoto Kyogoku, Yusaku Kudo, Yukiko Kudo, Inspector Megure, Miwako Sato, Wataru Takagi, Ninzaburo Shiratori, Chiba Kazunobu, Yumi Miyamoto, Naeko Miike, Kansuke Yamato, Yui Uehara, Takaaki Morofushi, Jugo Yokomizo, Sango Yokomizo, Kaito Kid, Saguru Hakuba, Momiji Ooka, Muga Iori, Masumi Sera, Mary Sera, Shuukichi Haneda, Eisuke Hondou, the Detective Boys, and many more.

The participants will witness videos, hidden truths, alternate timelines, impossible scenarios, memories, interviews, crossovers, future possibilities, and countless unexpected events.

No one knows who created the room.

No one knows why they were brought here.

The only certainty...

...is that the screen never lies.