Berial attacks Nero in the Ferrum Hills, a deserted mining camp. He claims to have visited the human world 2,000 years ago, and never met any human like Nero except for "him". After his defeat, he retreats from Nero to the demonic realm, but later returns to the Human World after Agnus opens the True Hellgate.

The next time he is seen, he is looking at the distant Savior in the sky and commenting on Sanctus' ridiculous arrogance. He doesn't notice Dante sitting on his tail until the Devil Hunter voices his agreement. After Berial shakes him off, he easily recognizes Dante as the infamous Son of Sparda, then claims that he will avenge his demonic compatriots slain by Dante. Though he is bested in battle, he refuses to retreat again, and launches a kamikaze attack which Dante repels. After Berial is defeated, Dante takes the Lucifer Devil Arm and destroys the Hell Gate from which Berial emerged. Nero battles Berial again while he's inside the Savior.

Berial has the lower body of a large bull, the legs and feet of a lizard or dragon, the upper body of a human, and a lion-like face, topped with vicious horns, and he towers above the single-story houses in the battlefield. His body is black, like cooled lava, with large, wing-like jets of flame sprouting from his humanoid shoulders and more flames cascading off his tail. When his flames are extinguished, these fires disappear and the creases in Berial's body take on more of a smouldering orange glow. In addition to his claws, Berial fights with a massive flaming sword, similar in appearance to a Zweihander, but his great size and strength allows him to wield it with a single hand. His attacks are slow, but powerful and with great reach; two aspects which no doubt helped him to conquer the Fire Hell.