Little is known about Wade's early years. His mother died of cancer when he was still young, and his father, a military man, reduced himself to a miserable state. During these years, Wade was a brawler until, while drinking with friends at a club, his father broke in and tried to take him out of the club, and then one of Wade's friends took possession of a gun and shot his father. After a short military service, Wade, before reaching adulthood, became a mercenary.

Little is known about Wilson's mercenary activities. In Japan, he was hired by a crime boss named Boss to infiltrate a sumo club owned by another criminal, Okata. Wilson spent three years as a competitor under the auspices of Okata. In the end, the Boss ordered the murder of Okata, but Wilson refused to complete the task, after which he fled to the United States. In America, Wilson met Vanessa Carlisle, a young and beautiful prostitute, and fell in love with her.

Deadpool served and was expelled from the ranks of the military or immediately became a mercenary. He worked for a crime boss in Japan for a while, then moved to the United States. Here he found shelter, fell in love and tried to find happiness. At the wrong moment, the hero was diagnosed with cancer.

Deadpool, like Wolverine, was subjected to experiments or voluntarily agreed to mutation under the guidance of William Stryker. Numerous experiments led to the fact that Deadpool got rid of the disease, but his psyche and appearance were damaged. Under the influence of mutation, he gained specific abilities in the form of rapid cell regeneration and immortality. Subsequently, the hero turned out to be an outstanding mercenary.