Chloe Frazer is one of the main characters of the Uncharted franchise. She serves as the tritagonist overall in the video game series, making her debut as one of the two deuteragonists of Uncharted 2: Among Thieves where she is one of Nathan Drake's love interests. She subsequently appears in Uncharted 3: Drake's Deception, in which she serves as a supporting character in the first half of the game, and is referenced in Uncharted 4: A Thief's End before becoming the playable main protagonist of Uncharted: The Lost Legacy. She also appears in the Uncharted film serving as the tritagonist, played by Sophia Ali.

She is an Indian-Australian treasure hunter and thief for hire; she's a skilled professional whose reputation often makes her highly demanded in the criminal underworld. She was also an associate, a major ally, and a former love interest to fellow treasure hunter Nathan Drake, and has also worked with other people such as Harry Flynn, Charlie Cutter, Nadine Ross, and Samuel Drake. In The Lost Legacy, it's revealed that she is half-Indian from her father's side.