Harley Quinn is an American adult animated black comedy superhero television series based on the DC Comics character of the same name created by Paul Dini and Bruce Timm. The series is written and executive-produced by Justin Halpern, Patrick Schumacker, and Dean Lorey, and follows the adventures of Harley Quinn and her best friend and partner Poison Ivy after leaving her boyfriend, the Joker. The show premiered on November 29, 2019.

The series follows the adventures of Harley Quinn and her journey of self-discovery after breaking up with the Joker upon realizing that he never loved her. Harley intends to make a name for herself in Gotham City's criminal underworld, starting with the formation of her own crew, which consists of her best friend now wife Poison Ivy, Clayface, Doctor Psycho, King Shark, and Sy Borgman.[1] During her attempts to prove herself as a competent villain, Harley faces her troubled past, gains self-confidence that helps her abolish the Joker's influence on her, and finds an autonomous identity.

In addition to the adventures of Harley's crew, the main storyline revolves around the relationship between Harley and Ivy. Having met in Arkham Asylum when Harley was Dr. Harleen Quinzel and Ivy's therapist, the two developed a strong friendship that gradually deepened over the course of the series. They eventually realize they have feelings for each other despite Ivy's initial insecurity and her engagement with Kite Man. After a series of misadventures, during which Harley proves her selfless love to Ivy and Kite Man breaks up with her in favor of Ivy's happiness, Harley and Ivy become a couple by the end of season two. Over later seasons, the pair experience what it is to be in a healthy romantic relationship with mutual support, honesty, and self-determination.[2]

As the series progresses, more DC characters gain a bigger role in the story, primarily the members of the Bat Family and members of the Legion of Doom as Harley and Ivy figure out their respective goals regarding those affiliations. Harley realizes she wants to help people rather than hurting them while Ivy discovers the true potential of her superpowers and develops a social conscience.

Apart from Harley and Ivy, other members of Harley's crew begin to follow their own path; Clayface breaks out as an actor, King Shark becomes a father and the ruler of the Shark Kingdom, and Psycho starts his own self-help podcast. Most of the seasons also contain a standalone episode that does not feature Harley or Ivy but focuses on one of the supporting characters, such as Joker, Batman, or Bane.