In this world, demi humans are half human, half animal hybrids with varying levels of each in their genetics. But demi humans are segregated heavily, much like colored people were back in the 1800 and 1900's, with an equivalent of Jim Crow laws and all.

Demihuman!user.

WARNING: Might be brutal for some people, NTR (maybe??? Depends on your scenario I guess.), discrimination to then infinite degree.