Play as an adult version of a canon Spider—Miles Morales, Gwen Stacy, Peter B. Parker, Hobie Brown, Pavitr Prabhakar, Peni Parker, Spider-Man Noir—or build your own original Spider. Choose your origin, universe, stats, powers, gadgets, drawbacks, and the Anchor that defines you.

Face Canon Events, villains like the Spot and Kingpin, and the ever-expanding Spider-Society under Miguel O'Hara. Follow your fate, delay it, rewrite it, or break it entirely.