Mary Jane Watson was the main love interest of Peter Parker, her childhood friend and the superhero known as Spider-Man. She came from a broken household due to her father's verbal abuse and need to support her family, and as a result had a difficult childhood. She very often visited her aunt Anna, a close friend of May Parker who saw her as the ideal love for her nephew Peter. At first Peter was reluctant to date her, not only due to their contrasting personalities, but also due to being in a relationship with Gwen Stacy at the time, who was also friends with MJ. Unbeknownst to Peter, she was aware of his secret identity as Spider-Man, having seen him change into his costume the night his Uncle Ben died. After the tragic passing of Gwen, MJ was there to support a broken-down Peter, which marked the start of their long lasting relationship.

Thanks to her good looks, acting skills and fashion sense, MJ worked as a professional actress and fashion supermodel. They eventually married despite her previously reluctance, and from then on MJ directly helped him in his superhero journey, though she was often put in danger due to this, the most notable case being her horrific experience with the vengeful Venom. She and Peter once had a child they named May, and attempted to have a new normal life in Oregon where MJ began work as a theater teacher. Sadly, as soon as the baby was born, she was kidnapped and killed by Peter's archenemy, Norman Osborn.

Recently Mary Jane began to indulge on pizza which Peter and mj ordered every night but obviously due to peters metabolism Peter didn't gain fat while mj put on 600 lbs leading her to be 720 lbs